Olympic Scorecard

Here are the current standings in the 2008 Beijing Olympics doping league.

Before the Games, Russia withdrew two walkers and a cyclist over positive test or suspicion of doping.   Bulgaria withdrew its entire weightlifting team due to positive tests for steroids.  The Greek weightlifting team also had numerous steroid positives.

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Classic paper - Meiotic mutants also affect mitosis

The utilization during mitotic cell division of loci controlling meiotic recombination and disjunction in Drosophila melanogaster.
Bruce S. Baker, Adelaide T. C. Carpenter, and P. Ripoll 
Genetics 1978 90: 531-578. [Abstract] [PDF]

As a postdoc, I worked for several years on the cell cycle in Drosophila.  At that time, the field was just beginning to take off, not least because of the efforts of my then group leader.  Nowadays, I study the ageing process, still using Drosophila, and including modelling the function of WRN, the gene responsible for the progeroid condition Werner's syndrome (WS). WRN encodes a RecQ DNA helicase (unwinds the DNA double helix), but unusually has a second activity, a DNA exonuclease (removes nucleotide bases from the end of a DNA strand). We are currently studing the Drosophila homologue of the WRN exonuclease (which we have named DmWRNexo, and which is encoded by the CG7670 locus).

When trying to demonstrate that a mutant of CG76700 indeed displayed characteristic comparable with defects seen in cell lines derived from WS patients, I recalled reading this paper at the beginning of my postdoc position.

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Chiropractors vs Singh

The Quackometer and Holfordwatch blogs report that the British Chiropractic Association, presumably fired by their New Zealand colleagues' attempts to silence scientific opinion, have filed a suit against Simon Singh following an article originally published in the Guardian (but now unavailable).  Hopefully this will engender a major Streisand effect, and I fully expect the case to fail.

See also the news report in the Telegraph (I notice the Telegraph journalists refer to the chiropractors as "Doctors" and doubt this is justified).

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Duo Normand preview 21/9/08

This year's Duo Normand time trial will be held on 21st September, and after a year's absence, Team Grumpy (a.k.a. Gerry Oram and me) will be competing again.  For a change, we are entered in the Corporate category instead of the Veteran category (we may revert to veteran if we continue to be the sole team in our category!).

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NBRC Club 10 13/8/08, Astwood

The 20 riders who turned out for this event were fortunate that we managed to avoid the heavy showers (some extremely heavy) that plagued us during the day.  We did however suffer strong winds that made the opening leg to Chicheley something of a trial, and aero wheel handling quite twitchy at times.

I didn't hang around after the event, as it was getting darker and windy.  I also didn't see most of the guys for the pre-race banter as I was quite late getting up to Astwood - I assume Gilbert ("Hard man of the North") Wheelwright is still using the tribars and pointy hat!  Stuart Tarry's winning time of 22:55 was pretty quick for an evening like this (even if he claimed he only showed up because I was going to give him an entry for his '10' on 30th August- which I forgot anyway).

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Prince Charles' startling outburst against GM food

The Daily Telegraph reports an interview with Prince Charles, that famous organic farmer, where he continues to lambast genetically modified crops.

His criticisms seem to principally concern the mass commercialisation of farming - I guess his interests in organic community farming in Caithness and the Duchy estate prompt this.  However the interview seems to me to be interpreted by the media as a criticism of the GM industry, despite his comments being vague and really quite ill-informed scientifically. To say GM crops are a "gigantic experiment I think with nature and the whole of humanity which has gone seriously wrong" is really unhelpful, with no evidence presented to support his stance.

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Normandy 2005

 These photographs were taken during the 2005 trip to Normandy for the Duo Normand.  They were taken before and after the race while tandem cycling in the Norman countryside, and during the race as we started in and passing through Marigny (notice the picture where we were going so fast only the edge of my disc wheel is in the photo!).  We also visited Mont St Michel.

{gallery}2005-normandy:::{/gallery} 

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Einsturzende Neubauten - Silence is Sexy

Einsturzende Neubauten have released a significant catalogue of music, which has metamorphosed from loud metal bashing to more sophisticated sounds such as Silence is Sexy, from the album of the same title.  I found this video at YouTube.

 

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Finsbury Park CC '25' F1/25 10/8/08

This was a particularly tough morning on the F1/25 - perhaps the hardest I can recall, though at least the heavy rain we saw on Saturday did not make a reappearance.

 The initial section, roughly southbound to the Sandy RAB, gave me a little taster for what was to come later on: after descending the sliproad to the A1, it was most definitely going to be tough on both southbound legs. Unfortunately the reverse didn't seem to the true, while it's true I was whizzing along with a tailwind after the Sandy RAB (I topped 34mph at times), the benefits of the wind seemed to be absent some of the time.  Presumably this was due to the slightly serpentine nature of the course.  Despite most peoples' opinion, I'm a bit of an optimist, and usually on days like this I reach the turn think that maybe, just maybe, the return leg won't be as hard as I expect.  For today's event, I can safely say the return leg exceeded my direst prognostications.  On some of the more exposed sections, I was battered down below 20mph, and I'm sure I saw 17mph at one point.  (Jason Gurney claimed afterwards to have had to drop to the small ring at one point!).  I was caught by #90 for 3 minutes shortly after the turn, and even he seemed to be struggling into the wind after that.

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2005 Cycle tour photo gallery

These photos were taken during our 2005 cycle tour of Uist, Harris and Skye.  Visit the tour description to see the context of these images.

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